Endoplasmic Reticulum

 

endoplasmic reticulum
Endoplasmic Reticulum (ER)


Endoplasmic Reticulum (ER) is a system of sac like structures and tubes found in all eukaryotic cells. They are known as sarcoplasmic reticulum in skeletal muscles, Nissl granules in neurons and myeloid bodies in retinal pigment cells.

They are absent in RBCs, eggs and embryonic cells.

Endoplasmic Reticulum arise by evagination of nuclear membrane.

Endoplasmic Reticulum have three parts:
  • Cisternae: It is a sac like, parallel tubules having ribosomes on their surface. It is unbranched.
  • Tubules: It is tube like, irregular, branched and without ribosome.
  • Vesicles: They are round or spherical, without ribosomes

Parts of Endoplasmic Reticulum


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There are two types of endoplasmic reticulum 
  1. Rough Endoplasmic Reticulum (RER): They have ribosomes on their surface. The 60S unit of ribosomes are attached to the ER by means of a protein ribophorin I and ribophorin II. Number of cisternae and tubules are more. They are abundant near the nuclear membrane. They are rich in protein secreting cells. e.g. plasma cells, goblet cells, fibroblasts, pancreatic cells and liver cells.
  2. Smooth Endoplasmic Reticulum (SER): They are devoid of ribosome. Number of tubules and vesicles are more. They are abundant near the plasma membrane and golgi complex. They are rich in lipid and sterol secreting cells. They also synthesize carbohydrates, vitamin C and helps in detoxification of pollutants and carcinogens.
Functions of Endoplasmic Reticulum:
  • Provide mechanical support to the cell.
  • Helps in intracellular transport.
  • Enzymes of ER helps in metabolic activities.
  • Helps in synthesis of nuclear envelope.


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